Rotavirus (RV) is a disease that is extremely spreadable in children whose age ranges between 3–5 years. Rotavirus vaccination (RVV) is an effective method for combating the diarrhoea disease as rotavirus is the leading cause of diarrhoea worldwide. For fulfilling the aim of reducing the burden of RV caused in children under 5 years for diarrhoea mortality. World Health Organization (WHO) recommends introducing RVVs worldwide. Globally three RVVs are licensed for local use; two monovalent vaccines Rotarix, and Rotavac and a pentavalent vaccine RotaTeq. Safety and efficacy of these vaccines have been proved, however, they require cold-chain storage at or below 2oto 8oC before use. In this article, a detailed profile of Rotarix vaccine is being emphasized. Rotavirus Vaccines are in high demand for introduction by many low-income countries, but limitations such as price, poor supply and insufficient cold-chain capacity at distant delivery points, have restricted their introduction.
Rotavirus, Rotavirus vaccination (RVV), Rotarix
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